Dr. Xiaoying Zhu is an optometrist and ophthalmologist with experience treating ocular disease. She has been an assistant clinical professor at SUNY Optometry since 2015. Previously Dr. Zhu served as an adjust assistant professor at the City University of New York and a research associate at the City University of New York’s Research Foundation. She was also an attending ophthalmologist at First Hospital at China Medical University.
Pediatric Eye Care - Myopia Control
Member of the Association for Research in Vision and Ophthalmology
School of Psychology, University of Newcastle, Callaghan, NSW, Australia, PhD, 2013–2017
New England College of Optometry, Boston, MA, OD, 2013–2015
Dept of Ophthalmology, the First Hospital, CMU, China, MS, 1995–1998
China Medical University (CMU), China, MD, 1987–1993
Biological and Vision Sciences, SUNY College of Optometry, 2015 – present
Assistant Clinical Professor, Lead Clinician, Myopia Control Clinic
Research Foundation of City University of New York, NY, NY, 1999 – 2013
Postdoctoral fellow / Research Associate
Dept. of Ophthalmology, First Hospital, China Medical University, 1993 – 1999
Ophthalmology Resident / Attending Ophthalmologist
Academic Honors and Awards
NIH Loan Repayment Program Award, 2016–2018
Fellow of the American Academy of Optometry (FAAO), 2016
Australian Research Training Program Scholarship, 2013–2016
As a clinician scientist, my principle research interest is in emmetropization, temporal integration of visual signals, and myopia control. I am currently conducting clinical trials to study the effect of contact lenses in slowing down myopia progression in school-aged children.
I have been studying the visual input and possible signaling molecules regulating emmetropization and eye growth. During my early Postdoctoral Fellowship while working at the Research Foundation of City University of New York, my research (under the guidance of the late Josh Wallman) focused on the potency of myopic defocus in both inducing axial and choroidal compensation for positive lenses and preventing negative lens compensation using the chick model. This finding was widely cited in the scientific press and has been repeated in other species, e.g., tree shrews, rhesus monkeys, and guinea pigs. More importantly, it laid the foundation for developing clinical measures to prevent myopia progression in school-aged children, using Progressive Addition Lenses / Bifocal Lenses, Multifocal soft contact lenses, both of which originally designed to correct presbyopia, and Orthokeratology. In addition, I also investigated the potential signaling molecules controlling eye growth, and studied the effects of two antagonizing molecules, glucagon and insulin, in emmetropization and lens compensation. To locate the site of action for insulin, I developed a novel model, eye cup, to study the effects of insulin in various ocular tissue layers. The findings (glucagon and insulin prevent negative and positive lens compensation, respectively) have great potentials in developing pharmacological measures to prevent myopia. The eye cup model has been used by other laboratories. I also collaborated with Dr. Debora Nickla (at New England College of Optometry) to study the effects of muscarinic agents in eye growth.
Temporal Integration of Visual Signals
After discovering the potency of myopic defocus, I further explored the integration of visual signal in eye growth by investigating the temporal integration of myopic and hyperopic defocus, using the chick and marmoset models. My results show striking findings that both explain the potency of myopic defocus (the signal controlling axial inhibition after wearing positive lenses is very long lasting) and provide important clinical information in myopia prevention (taking frequent breaks during near work should help reduce myopia development). My findings have been repeated in guinea pigs and marmosets, and inspired the invention of multiple equipment (e.g., ClouClip) to look into temporal properties during near work in children.
Orthokeratology and multifocal soft contact lenses have been shown to be efficacious in reducing myopia progression in school-aged children by superimposing myopic defocus (as a stop signal) in front of the peripheral retina. I am currently conducting clinical trials to study the effect of contact lenses in slowing down myopia progression in school-aged children.
Australian Research Training Program Scholarship, 2013-2016
Schnurmacher Institute for Vision Research funding, 2018-present